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From Lynchburg, Altavista, and Hurt on Route 29 S:

• Take Route 29 S to Gretna.
• On Route 29 S take the Route 40 exit which also goes toward Smith Mountain Dam.
• On the exit ramp at the intersection with Route 40 W (West Gretna Road), turn right.
• On West Gretna Road look for the Centra Health Medical Center - Gretna,immediately on the right at 1220 West Gretna Road.

From Danville, Blairs, and Chatham on Route 29 N:

• Take Route 29 N to Gretna.
• On Route 29 proceed to the second Gretna exit on the right. This exit also goes to Route 40 and Smith Mountain Dam.
• Turn left onto Route 40 W (West Gretna Road), go over the overpass for Route 29 bypass.
• On Route 40 (West Gretna Road), look for Centra Health Medical Center -Gretna, immediately on the right at 1220 West Gretna Road.

From Rocky Mount, Gladehill, Union Hall,and Penhook on Route 40 E:

• Take Route 40 E to Gretna.
• Watch for the Dairy Queen Restaurant near Gretna.
• At the second driveway on the left past the Dairy Queen Restaurant, look for Centra Health Medical Center - Gretna at 1220 West Gretna Road.

From Brookneal, Cody, and Mt. Airy on Route 40 W:

• Take Route 40 W to the stoplight at Gretna which is at the junction of Route 40 and Route 29 Business.
• Continue West on Route 40 W passing over Route 29 Bypass.
• After passing over Route 29 bypass, look for Centra Health Medical Center - Gretna, immediately on the right at 1220 West Gretna Road.